The knee joint consists of an articulation between four bones: the femur, tibia, fibula and patella. There are four compartments to the knee. These are the medial and lateral tibiofemoral compartments, the patellofemoral compartment and the superior tibiofibular joint. The components of each of these compartments can suffer from repetitive strain, injury or disease.
Running long distance can cause pain to the knee joint, as it is high-impact exercise.
Some common injuries include:
- Sprain (Ligament sprain)
- Tear of meniscus
- Strain (Muscle strain)
- Hemarthrosis – Hemarthrosis tends to develop over a relatively short period after injury, from several minutes to a few hours.
Some of the diseases of cause of knee pain include the following:
- Knee osteoarthritis
- Chondromalacia patella
- Baker’s cyst
- Meniscal cyst
- Discoid meniscus
- Osgood-Schlatter disease
- Larsen-Johansson disease
- Knee rheumatoid arthritis
- Osteochondritis dissecans disease
- Synovial chondromatosis disease
- Ankylosing spondylitis
- Reactive arthritis
- Tuberculosis arthritis
- Septic arthritis (Pyogenic arthritis)
- Hemophilic arthritis
- Gout (Gouty arthritis)
- Bursitis of the knee
- Synovitis of the knee
Common deformities of the knee include:
- Bipartite patella (two-part kneecap)
- Genu varum (bow legs)
- Genu valgum (knock-knees)
- Genu recurvatum (Knee hyperextension)
- Knee flexion deformity
- Patellofemoral pain syndrome
- Plica syndrome
- Iliotibial band syndrome
- Hoffa’s syndrome
- Joint hypermobility syndrome
Knee pain is more common among people working in the cold than in those in normal temperature. Cold-induced knee pain may also be due to tenosynovitis of the tendons around the knee, in which cold exposure has a specific role, either as a causative or a contributing factor. Frank arthritis has been reported in children due to frostbite from extreme cold causing direct chondrocyte injury.
There is also a hereditary disease, familial cold autoinflammatory syndrome (FCAS), which often features knee pain, in addition to hives, fever and pain in other joints, following general exposure to cold.
Knee pain due to less physical movement
A lower level of physical activity and a work environment where one is required to sit in a chair during the work day is one reason for developing knee joint pain, as the lower degree of physical movement tends to weaken the knee muscles. Blood vessels also can be affected, leading to development of painful conditions.
As age progresses the movement of the knee joint involves higher friction with adjacent tissue and cartilages.
- Ligamentous laxity
- Fat pad impingement
- Knee effusion
- Deep vein thrombosis
- Peripheral vascular disease
Referred knee pain
Referred pain is that pain perceived at a site different from its point of origin but innervated by the same spinal segment. Sometimes knee pain may be related to another area from body. For example, knee pain can come from ankle, foot, hip joints or lumbar spine.
In some diagnosis, such as in knee osteoarthritis, magnetic resonance imaging does not prove to be clear for its determination 
Although surgery has a role in repairing traumatic injuries and broken bones, surgeries such as arthroscopic lavage do not provide significant or lasting improvements to either pain or function to people with knee pain, and therefore should almost never be performed. Knee pain is pain caused by wear and tear, such as osteoarthritis or a meniscal tear. Effective treatments for knee pain include physical therapy exercises, pain-reducing drugs such as ibuprofen, joint stretching, knee replacement surgery, and weight loss in people who are overweight.
Acupuncture has also been found to be a potential treatment for those with knee pain. There is evidence that acupuncture can be useful in reducing acute pain after a total knee arthroplasty, reducing the need for certain prescription drugs such as opioids. For those suffering from chronic knee pain, defined as pain lasting more than 3 months, acupuncture was found to be effective in reducing pain up to 12 weeks after acupuncture treatment.
Overall, a combination of interventions seems to be the best choice when treating knee pain. Interventions such as exercises that target both the knee and the hip, foot bracing, and patellar taping are all recommended for use with patients suffering from knee pain.
Current evidence suggests that psychological factors are elevated in individuals with patellofemoral pain. Non-physical factors such as anxiety, depression, fear of movement, and catastrophizing are thought to have a linear correlation with increased pain experience and decreased physical function. Catastrophizing is defined as imagining the worst possible outcome of an action or event. Furthermore, psychosocial factors may have either a positive or negative impact on adherence to rehabilitation programs for managing knee pain.
About 25% of people over the age of 50 experience knee pain from degenerative knee diseases.
Society and culture
In the United States, more than US $3 billion is spent each year on arthroscopic knee surgeries that are known to be ineffective in people with degenerative knee pain.
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